| 1540-41 | DeSoto camps in Indian village here during the winter (local legend) | Goodspeed, 767. |
| 1784 | Land explorers pass through this section. | Goodspeed, 767. |
| 1793 | North Carolina land grants issued here. | Goodspeed, 767. |
| Spring 1806 | Tennessee surveying party passes through. | Goodspeed, 767. |
| Fall 1806 | Ezekiel Norris probably first permanent white settler. | Goodspeed, 768. |
| 1809-10 | Davy Crockett lives on West Branch of Mulberry Creek. | Goodspeed, 768. |
| 1809 | County established effective 1 Jan 1810. Militia form the 39th Regiment attached to the 5th Brigade. | Goodspeed, 775. |
| 1810 | First County Jail erected. | Goodspeed, 775. |
| 1811 | First permanent Court House erected. | Goodspeed, 775. |
| 1812? | 2,000 troops rendevouz in Fayetteville and march off to war. | Goodspeed, 775. |
| 1820 | Federal census: population is 14,963. | Waller, 1820 census. |
| 1826 | Poor Farm established and Poor House erected. | Goodspeed, 772. |
| 1830 | Mulberry Academy established. | Goodspeed, 780. |
| 1835 | County divided into 25 Civil Districts. | Waller, 1840 census, 109. |
| 1836 | One company forms and marches off to war. | Goodspeed, 775. |
| 1840 | Federal census: population is 21,497. | Waller, 1840 census, 108. |
| 1846 | One company of 83 men (the Lincoln Guard) enlist. Several members killed at the Battle of Monterey. | Goodspeed, 775. |
| 1850 | Fayetteville Observer (newspaper) established. | Goodspeed, 779. |
| 1858 | Fayetteville connected to Nashville & Chattanooga Railroad by branch line to Decherd. | Goodspeed, 772. |
| 1861 | 450 foot stone arch bridge built over the Elk River. | Goodspeed, 772. |
| 1861 | 2,892 vote for separation, 0 for no separation. | Goodspeed, 775. |
| 1861 | Four companies join Turney's 1st Tennessee Regiment | Goodspeed, 775. |
| 1861 | Four companies join Fulton's 8th Tennessee Regiment | Goodspeed, 776. |
| 1861 | Two companies join the 32nd Tennessee Regiment | Goodspeed, 776. |
| 1861 | Four companies join Farquharson's 41st Tennessee Regiment | Goodspeed, 776. |
| 1861 | Four companies join McDaniel's 44th Tennessee Regiment | Goodspeed, 776. |
| 1861 | One company joins the 55th Tennessee Regiment | Goodspeed, 777. |
| 1862 | One company joins a Kentucky Regiment | Goodspeed, 777. |
| 1862 | One company formed by J.L. Moore as last full company to enter war. | Goodspeed, 777. |
| 1862 | Freeman's Battery, part of Hardin's Artillery receives 50 county men. | Goodspeed, 777. |
| 1862 | Majority of Forrest's escort are county men. | Goodspeed, 777. |
| 1862 | Federals occupy Fayetteville April 9th, withdrawing within two months. | Goodspeed, 777. |
| 1863 | Federals re-occupy Fayetteville remaining until 1865 (some county records destroyed). | Goodspeed, 777. |
| 1864? | Sherman's Army marches through Fayetteville. | Goodspeed, 777. |
| 1868 | New Jail House erected. | Goodspeed, 772. |
| 1873 | Original Court House torn down and replaced. | Goodspeed, 772. |
| 1882 | Narrow gauge railroad built from Columbia to Fayetteville. | Goodspeed, 772. |
