Margaret Alyssa O’Brien, 55, died Saturday, October 23, 2010 at her residence in Hohenwald.  She was born December 24, 1954 in Richmond, Virginia to Homer Pickrel and the late Pauline Wilkerson Pickrel.  In addition to her father, she is survived by two sons, Christopher O’Brien and Jarrett Hinson, both of Hohenwald; two daughters, Rebecca Hinson and Raina O’Brien, also of Hohenwald; and one brother, Steven Pickrel of Florida.  McDonald Funeral Home was in charge of arrangements.